The actor, who played lovable coffee shop manager Gunther, passed away at his home in Los Angeles at the age of 59 after his battle with cancer.
His co-stars were quick to pay tribute, including Jennifer Aniston – whose character Rachel was the apple of Gunther's eye.
When Friends ended, Gunther travelled the world making appearances and opening replica Central Perks.
He also won roles on other sitcoms such as Scrubs, Sabrina the Teenage Witch, Modern Music and Anger Management – and even teamed up with Matt Le Blanc in 2012 for his show Episodes.
James revealed he'd been battling stage 4 prostate cancer since 2018 in June, after doctors discovered the disease during a routine physical exam.
James' character Gunther was part of a big supporting cast in Friends, from Chandler's annoying girlfriend Janice to Ross' lesbian ex-wife Carol.
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